Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.

Neuropilin-1 (Nrp-1) expression on CD8+ T cells has been identified in tumor-infiltrating lymphocytes and in persistent murine gamma-herpes virus infections, where it interferes with the development of long-lived memory T cell responses. In parasitic and acute viral infections, the role of Nrp-1 exp...

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Main Authors: Hanna Abberger, Matthias Hose, Anne Ninnemann, Christopher Menne, Mareike Eilbrecht, Karl S Lang, Kai Matuschewski, Robert Geffers, Josephine Herz, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011837