Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing

Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing

Bone defect healing is markedly impaired in osteoporotic patient due to poor bone regeneration ability. Stromal cell derived factor-1α (SDF-1α) plays a pivotal role in the repair of various injured tissues including bone. Here, we definite that SDF-1α hydrogels potentiates in vivo osteogenesis of bo...

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Détails bibliographiques
Auteurs principaux: Qian Liu, Yi Wen, Jun Qiu, Zhaoyichun Zhang, Zuolin Jin, Meng Cao, Yang Jiao, Hongxu Yang
Format: Article
Langue:English
Publié: Elsevier 2020-06-01
Collection:Heliyon
Sujets:
Osteoporosis
Bone defects
BMSCs
SDF-1α
Osteogenesis
Regeneration
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2405844020311919

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020311919

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