Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing

Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing

Bone defect healing is markedly impaired in osteoporotic patient due to poor bone regeneration ability. Stromal cell derived factor-1α (SDF-1α) plays a pivotal role in the repair of various injured tissues including bone. Here, we definite that SDF-1α hydrogels potentiates in vivo osteogenesis of bo...

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Detalles Bibliográficos
Main Authors: Qian Liu, Yi Wen, Jun Qiu, Zhaoyichun Zhang, Zuolin Jin, Meng Cao, Yang Jiao, Hongxu Yang
Formato: Artigo
Idioma:English
Publicado: Elsevier 2020-06-01
Series:Heliyon
Subjects:
Osteoporosis
Bone defects
BMSCs
SDF-1α
Osteogenesis
Regeneration
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2405844020311919

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020311919

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