Naringin Mediates Adult Hippocampal Neurogenesis for Antidepression via Activating CREB Signaling

Naringin Mediates Adult Hippocampal Neurogenesis for Antidepression via Activating CREB Signaling

The brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response element-binding protein (BDNF/TrkB/CREB) signaling pathway is a critical therapeutic target for inducing adult hippocampal neurogenesis and antidepressant therapy. In this study, we tested the hypothesis that naringin,...

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Bibliographic Details
Main Authors: Chong Gao, Meiling Wu, Qiaohui Du, Jiagang Deng, Jiangang Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
depression
adult hippocampal neurogenesis
naringin
BDNF pathway
CREB
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.731831/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.731831/full

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