NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes

NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes

Steroid-resistant nephrotic syndrome (SRNS) frequently leads to end-stage renal disease, ultimately requiring kidney replacement therapies. SRNS is often caused by hereditary monogenic mutations, specifically affecting specialized epithelial cells (podocytes) of the glomerular filtration barrier. Mu...

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Bibliographic Details
Main Authors: Manuel Rogg, Jasmin I. Maier, Markus Ehle, Alena Sammarco, Oliver Schilling, Martin Werner, Christoph Schell
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
NUP133
nuclear pore complex
nucleoporin
podocyte
SRNS
podocytopathy
Online Access:https://www.mdpi.com/2073-4409/11/8/1259

Internet

https://www.mdpi.com/2073-4409/11/8/1259

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