In celebration of a century with insulin – Update of insulin gene mutations in diabetes

Background: While insulin has been central to the pathophysiology and treatment of patients with diabetes for the last 100 years, it has only been since 2007 that genetic variation in the INS gene has been recognised as a major cause of monogenic diabetes. Both dominant and recessive mutations in th...

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Bibliographic Details
Main Authors: Julie Støy, Elisa De Franco, Honggang Ye, Soo-Young Park, Graeme I. Bell, Andrew T. Hattersley
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001253