Abnormal Ferroptosis in Myelodysplastic Syndrome

Abnormal Ferroptosis in Myelodysplastic Syndrome

BackgroundFerroptosis is a form of iron-dependent non-apoptotic cell death, with characteristics of loss of the activity of the lipid repair enzyme, glutathione (GSH) peroxidase 4 (GPX4), and accumulation of lethal reactive lipid oxygen species. The mechanism of ferroptosis in myelodysplastic syndro...

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Bibliographic Details
Main Authors: Qi Lv, Haiyue Niu, Lanzhu Yue, Jiaxi Liu, Liyan Yang, Chunyan Liu, Huijuan Jiang, Shuwen Dong, Zonghong Shao, Limin Xing, Huaquan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
myelodysplastic syndrome
ferroptosis
decitabine
apoptosis
pyroptosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01656/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01656/full

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