Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair

Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair

As conventional treatments for diabetic wounds often fail to achieve rapid satisfactory healing, the development of effective strategies to accelerate diabetic wound repair is highly demanded. Herein, fibroblast growth factor 21 (FGF21) and metformin co-loaded multifunctional polyvinyl alcohol (PVA)...

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Bibliographic Details
Main Authors: Hong Zhu, Jie Xu, Min Zhao, Hangqi Luo, Minjie Lin, Yuting Luo, Yuan Li, Huacheng He, Jiang Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
PVA
FGF21 (fibroblast growth factor 21)
diabetic wound
ROS
hydrogels
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.968078/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.968078/full

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