The response of CD27+CD38+ plasmablasts, CD24hiCD38hi transitional B cells, CXCR5−ICOS+PD-1+ Tph, Tph2 and Tfh2 subtypes to allergens in children with allergic asthma

The response of CD27+CD38+ plasmablasts, CD24hiCD38hi transitional B cells, CXCR5−ICOS+PD-1+ Tph, Tph2 and Tfh2 subtypes to allergens in children with allergic asthma

Abstract Background Allergic asthma is a type I allergic reaction mediated by serum Immunoglobulin E (IgE). B cell-mediated humoral immune response to allergens in the pathophysiology of allergic asthma have not been thoroughly elucidated. Peripheral helper T cells (Tph) and follicular helper T cell...

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Bibliographic Details
Main Authors: Yunying Zhu, Qian Jiang, Chenshuang Lei, Qinhua Yu, Liannv Qiu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Pediatrics
Subjects:
Allergic asthma
Flow cytometry
B cell subsets
Peripheral helper T cell
IgE
Online Access:https://doi.org/10.1186/s12887-024-04622-4

Internet

https://doi.org/10.1186/s12887-024-04622-4

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