The Novel [4,5-e][1,3]Diazepine-4,8-dione and Acyclic Carbamoyl Imino-Ureido Derivatives of Imidazole: Synthesis, Anti-Viral and Anti-Tumor Activity Evaluations

The Novel [4,5-e][1,3]Diazepine-4,8-dione and Acyclic Carbamoyl Imino-Ureido Derivatives of Imidazole: Synthesis, Anti-Viral and Anti-Tumor Activity Evaluations

In the present paper, we report on the synthesis, and in vitro antiviral and cytostatic activities of a series of novel imidazole[4,5-e][1,3]diazepine-4,8-dione (compounds 9–11) and acyclic carbamoyl imino-ureido imidazole (compounds 12 and 13) derivatives. These new type of chemical entities showed...

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Bibliographic Details
Main Authors: Karlo Wittine, Kristina Poljak, Matea Kovač, Damjan Makuc, Janez Plavec, Jan Balzarini, Tamara Martinović, Sandra Kraljević Pavelić, Krešimir Pavelić, Mladen Mintas
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
imidazole
[4,5-e][1,3]diazepine
anti-RSV
anti-tumor
Online Access:http://www.mdpi.com/1420-3049/18/11/13385

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http://www.mdpi.com/1420-3049/18/11/13385

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