A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer

A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer

A widely used procedure for selecting significant miRNA-mRNA or isomiR-mRNA pairs out of predicted interactions involves calculating the correlation between expression levels of miRNAs/isomiRs and mRNAs in a series of samples. In this manuscript, we aimed to assess the validity of this procedure by...

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Bibliographic Details
Main Authors: Stepan Nersisyan, Anton Zhiyanov, Narek Engibaryan, Diana Maltseva, Alexander Tonevitsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Genetics
Subjects:
isomiR
miRNA
targeting
breast cancer
TCGA
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1070528/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1070528/full

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