Effect of mRNA-LNP components of two globally-marketed COVID-19 vaccines on efficacy and stability
Abstract During the COVID-19 pandemic, Pfizer-BioNTech and Moderna successfully developed nucleoside-modified mRNA lipid nanoparticle (LNP) vaccines. SARS-CoV-2 spike protein expressed by those vaccines are identical in amino acid sequence, but several key components are distinct. Here, we compared...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00751-6 |