Evaluation of in vivo MRI for detecting midodrine-induced arteritis in rats

There are no specific and sensitive biomarkers for arteritis, and the occurrence of arteritis in nonclinical toxicological studies of a candidate drug makes development of the drug very difficult. However, we showed in a previous study that the high signal intensity region around the artery on magne...

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Bibliographic Details
Main Authors: Yuta Fujii, Yuka Yoshino, Kazuhiro Chihara, Aya Nakae, Jun-ichiro Enmi, Yoshichika Yoshioka, Izuru Miyawaki
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221475002300001X