Analysis of lung cancer-related genetic changes in long-term and low-dose polyhexamethylene guanidine phosphate (PHMG-p) treated human pulmonary alveolar epithelial cells

Analysis of lung cancer-related genetic changes in long-term and low-dose polyhexamethylene guanidine phosphate (PHMG-p) treated human pulmonary alveolar epithelial cells

Abstract Background Lung injury elicited by respiratory exposure to humidifier disinfectants (HDs) is known as HD-associated lung injury (HDLI). Current elucidation of the molecular mechanisms related to HDLI is mostly restricted to fibrotic and inflammatory lung diseases. In our previous report, we...

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Bibliographic Details
Main Authors: Hong Lee, Sang Hoon Jeong, Hyejin Lee, Cherry Kim, Yoon Jeong Nam, Ja Young Kang, Myeong Ok Song, Jin Young Choi, Jaeyoung Kim, Eun-Kee Park, Yong-Wook Baek, Ju-Han Lee
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Pharmacology and Toxicology
Subjects:
Polyhexamethylene guanidine phosphate
Humidifier disinfectant
Human pulmonary alveolar epithelial cells
Total RNA sequencing
Lung cancer related genes
Online Access:https://doi.org/10.1186/s40360-022-00559-5

Internet

https://doi.org/10.1186/s40360-022-00559-5

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