Structural insights from random mutagenesis of <it>Campylobacter jejuni</it> oligosaccharyltransferase PglB

Structural insights from random mutagenesis of <it>Campylobacter jejuni</it> oligosaccharyltransferase PglB

<p>Abstract</p> <p>Background</p> <p>Protein glycosylation is of fundamental importance in many biological systems. The discovery of N-glycosylation in bacteria and the functional expression of the N-oligosaccharyltransferase PglB of <it>Campylobacter jejuni</i...

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Bibliographic Details
Main Authors: Ihssen Julian, Kowarik Michael, Wiesli Luzia, Reiss Renate, Wacker Michael, Thöny-Meyer Linda
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Biotechnology
Subjects:
glycosylation
oligosaccharyltransferase
PglB
<it>Campylobacter jejuni</it>
random mutagenesis
screening
ELISA
directed evolution
conjugate vaccine
Online Access:http://www.biomedcentral.com/1472-6750/12/67

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http://www.biomedcentral.com/1472-6750/12/67

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