Reshaping Intratumoral Mononuclear Phagocytes with Antibody‐Opsonized Immunometabolic Nanoparticles

Reshaping Intratumoral Mononuclear Phagocytes with Antibody‐Opsonized Immunometabolic Nanoparticles

Abstract Mononuclear phagocytes (MPs) are vital components of host immune defenses against cancer. However, tumor‐infiltrating MPs often present tolerogenic and pro‐tumorigenic phenotypes via metabolic switching triggered by excessive lipid accumulation in solid tumors. Inspired by viral infection‐m...

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Bibliographic Details
Main Authors: Chang Liu, Yanfeng Zhou, Daoxia Guo, Yan Huang, Xiaoyuan Ji, Qian Li, Nan Chen, Chunhai Fan, Haiyun Song
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
biomimetic nanoparticle
immunometabolic reshaping
innate immune stimulation
lipid metabolic reprogramming
mononuclear phagocyte
Online Access:https://doi.org/10.1002/advs.202303298

Internet

https://doi.org/10.1002/advs.202303298

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