Combining Miconazole and Domiphen Bromide Results in Excess of Reactive Oxygen Species and Killing of Biofilm Cells

Combining Miconazole and Domiphen Bromide Results in Excess of Reactive Oxygen Species and Killing of Biofilm Cells

Fungal biofilm-related infections are increasingly occurring. We previously identified a fungicidal antibiofilm combination, consisting of miconazole (MCZ) and the quaternary ammonium compound domiphen bromide (DB). DB eliminates tolerance rather than altering the susceptibility to MCZ of various Ca...

Full description

Bibliographic Details
Main Authors: Jana Tits, Judith Berman, Bruno P. A. Cammue, Karin Thevissen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
biofilm
Candida
combination treatment
fungicidal
miconazole
domiphen bromide
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.617214/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.617214/full

Similar Items