The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT The opportunistic pathogen Cryptococcus neoformans causes fungal meningoencephalitis in immunocompromised individuals. In previous studies, we found that the Hap complex in this pathogen represses genes encoding mitochondrial respiratory functions and tricarboxylic acid (TCA) cycle componen...

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Bibliographic Details
Main Authors: Mélissa Caza, Guanggan Hu, Michael Price, John R. Perfect, James W. Kronstad
Format: Article
Language:English
Published: American Society for Microbiology 2016-02-01
Series:mSphere
Subjects:
carbon metabolism
cell wall
macrophages
regulation
TOR kinase
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00080-15

Internet

https://journals.asm.org/doi/10.1128/mSphere.00080-15

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