Solitary neurofibroma over lower lip: A rare manifestation
Neurofibromas are common nerve sheath tumors, occurring either sporadically or associated with Von Recklinghausen’s disease. Only 6.5% of solitary lesions are seen to involve the oral cavity without any features of neurofibromatosis type 1 (NF-1). It presents as a soft, skin-colored nodule with a ch...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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Series: | Journal of Cutaneous and Aesthetic Surgery |
Subjects: | |
Online Access: | http://www.jcasonline.com/article.asp?issn=0974-2077;year=2022;volume=15;issue=2;spage=189;epage=192;aulast=Jartarkar |
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author | Shishira R Jartarkar B Spoorthy Sruthi Kareddy |
author_facet | Shishira R Jartarkar B Spoorthy Sruthi Kareddy |
author_sort | Shishira R Jartarkar |
collection | DOAJ |
description | Neurofibromas are common nerve sheath tumors, occurring either sporadically or associated with Von Recklinghausen’s disease. Only 6.5% of solitary lesions are seen to involve the oral cavity without any features of neurofibromatosis type 1 (NF-1). It presents as a soft, skin-colored nodule with a characteristic buttonhole invagination. Histologically, it is an unencapsulated lesion consisting of proliferated neural elements, with a background of mucin and mast cells. Surgical excision is the treatment of choice. A 49-year-old female patient presented with a 35-year history of single, asymptomatic lesion over the lower lip, with no features of NF-1. On the basis of the history, histopathological findings, and dermoscopy, a diagnosis of neurofibroma was made and the lesion was excised, with no recurrence over a period of 1 year. The present case report has been reported for its interesting presentation and unusual site of involvement. |
first_indexed | 2024-04-11T21:40:22Z |
format | Article |
id | doaj.art-7b7954cbf30e49f39fd691537cb7008f |
institution | Directory Open Access Journal |
issn | 0974-2077 |
language | English |
last_indexed | 2024-04-11T21:40:22Z |
publishDate | 2022-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Cutaneous and Aesthetic Surgery |
spelling | doaj.art-7b7954cbf30e49f39fd691537cb7008f2022-12-22T04:01:37ZengWolters Kluwer Medknow PublicationsJournal of Cutaneous and Aesthetic Surgery0974-20772022-01-0115218919210.4103/JCAS.JCAS_100_21Solitary neurofibroma over lower lip: A rare manifestationShishira R JartarkarB SpoorthySruthi KareddyNeurofibromas are common nerve sheath tumors, occurring either sporadically or associated with Von Recklinghausen’s disease. Only 6.5% of solitary lesions are seen to involve the oral cavity without any features of neurofibromatosis type 1 (NF-1). It presents as a soft, skin-colored nodule with a characteristic buttonhole invagination. Histologically, it is an unencapsulated lesion consisting of proliferated neural elements, with a background of mucin and mast cells. Surgical excision is the treatment of choice. A 49-year-old female patient presented with a 35-year history of single, asymptomatic lesion over the lower lip, with no features of NF-1. On the basis of the history, histopathological findings, and dermoscopy, a diagnosis of neurofibroma was made and the lesion was excised, with no recurrence over a period of 1 year. The present case report has been reported for its interesting presentation and unusual site of involvement.http://www.jcasonline.com/article.asp?issn=0974-2077;year=2022;volume=15;issue=2;spage=189;epage=192;aulast=Jartarkarlower-lipneurofibromasolitary |
spellingShingle | Shishira R Jartarkar B Spoorthy Sruthi Kareddy Solitary neurofibroma over lower lip: A rare manifestation Journal of Cutaneous and Aesthetic Surgery lower-lip neurofibroma solitary |
title | Solitary neurofibroma over lower lip: A rare manifestation |
title_full | Solitary neurofibroma over lower lip: A rare manifestation |
title_fullStr | Solitary neurofibroma over lower lip: A rare manifestation |
title_full_unstemmed | Solitary neurofibroma over lower lip: A rare manifestation |
title_short | Solitary neurofibroma over lower lip: A rare manifestation |
title_sort | solitary neurofibroma over lower lip a rare manifestation |
topic | lower-lip neurofibroma solitary |
url | http://www.jcasonline.com/article.asp?issn=0974-2077;year=2022;volume=15;issue=2;spage=189;epage=192;aulast=Jartarkar |
work_keys_str_mv | AT shishirarjartarkar solitaryneurofibromaoverlowerlipararemanifestation AT bspoorthy solitaryneurofibromaoverlowerlipararemanifestation AT sruthikareddy solitaryneurofibromaoverlowerlipararemanifestation |