Interleukin-1β modulates lymphoid differentiation of Flt3-positive multipotent progenitors after transplantation

Summary: Myeloablative pre-conditioning facilitates the differentiation of transplanted hematopoietic stem and progenitor cells (HSPCs). However, the factors in the stress environment that regulate HSPC behavior remain elusive. Here, we investigated the mechanisms that shaped the cell fates of trans...

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Bibliographic Details
Main Authors: Jing Xia, Lisi Lan, Chenyu You, Li Tang, Tao Chen, Yunqiao Yang, Li Lin, Jianlong Sun
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724012415