Optogenetic activation of mGluR1 signaling in the cerebellum induces synaptic plasticity

Optogenetic activation of mGluR1 signaling in the cerebellum induces synaptic plasticity

Summary: Neuronal plasticity underlying cerebellar learning behavior is strongly associated with type 1 metabotropic glutamate receptor (mGluR1) signaling. Activation of mGluR1 leads to activation of the Gq/11 pathway, which is involved in inducing synaptic plasticity at the parallel fiber-Purkinje...

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Bibliographic Details
Main Authors: Tatjana Surdin, Bianca Preissing, Lennard Rohr, Michelle Grömmke, Hanna Böke, Maike Barcik, Zohre Azimi, Dirk Jancke, Stefan Herlitze, Melanie D. Mark, Ida Siveke
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Behavioral neuroscience
Molecular neuroscience
Cellular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222021010

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http://www.sciencedirect.com/science/article/pii/S2589004222021010

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