Myosins and MyomiR Network in Patients with Obstructive Hypertrophic Cardiomyopathy

Myosins and MyomiR Network in Patients with Obstructive Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy. The molecular mechanisms determining HCM phenotypes are incompletely understood. Myocardial biopsies were obtained from a group of patients with obstructive HCM (n = 23) selected for surgical myectomy and from 9 unused dono...

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Main Authors: Chiara Foglieni, Maria Lombardi, Davide Lazzeroni, Riccardo Zerboni, Edoardo Lazzarini, Gloria Bertoli, Annalinda Pisano, Francesca Girolami, Annapaola Andolfo, Cinzia Magagnotti, Giovanni Peretto, Carmem L. Sartorio, Iacopo Olivotto, Giovanni La Canna, Ottavio Alfieri, Ornella E. Rimoldi, Lucio Barile, Giulia d’Amati, Paolo G. Camici
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
hypertrophic cardiomyopathy (HCM)
cardiomyocytes
myosin heavy chain (isoform: MyHC, gene: <i>MYH</i>)
microRNA (<i>miRs</i>)
MyomiR (myosin-encoded miRs)
<i>miR-499</i>
Online Access:https://www.mdpi.com/2227-9059/10/9/2180

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https://www.mdpi.com/2227-9059/10/9/2180

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