CTSB promotes sepsis-induced acute kidney injury through activating mitochondrial apoptosis pathway

CTSB promotes sepsis-induced acute kidney injury through activating mitochondrial apoptosis pathway

BackgroundAcute kidney injury is a common and severe complication of sepsis. Sepsis -induced acute kidney injury(S-AKI) is an independent risk factor for mortality among sepsis patients. However, the mechanisms of S-AKI are complex and poorly understand. Therefore, exploring the underlying mechanism...

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Bibliographic Details
Main Authors: Yuting Wang, Wenjie Xi, Xinyi Zhang, Xinwen Bi, Boyang Liu, Xiaoming Zheng, Xinjin Chi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
lysosomal membrane permeabilization
CA074
mitochondrial apoptosis pathway
S-AKI
cathepsin B (CTSB)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1053754/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1053754/full

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