Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

Abstract Acute myeloid leukemia (AML) remains an incurable malignancy despite recent advances in treatment. Recently a number of new therapies have emerged for the treatment of AML which target BCL-2 or the membrane receptor CD38. Here, we show that treatment with Venetoclax and Daratumumab combinat...

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Bibliographic Details
Main Authors: Jayna J Mistry, Charlotte Hellmich, Amelia Lambert, Jamie A Moore, Aisha Jibril, Angela Collins, Kristian M Bowles, Stuart A Rushworth
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Biomarker Research
Online Access:https://doi.org/10.1186/s40364-021-00291-y

Internet

https://doi.org/10.1186/s40364-021-00291-y

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