Clinical decision support analysis of a microRNA-based thyroid molecular classifier: A real-world, prospective and multicentre validation study

Summary: Background: The diagnosis of cancer in Bethesda III/IV thyroid nodules is challenging as fine-needle aspiration (FNA) has limitations, and these cases usually require diagnostic surgery. As approximately 77% of these nodules are not malignant, a diagnostic test accurately identifying benig...

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Main Authors: Marcos Tadeu Santos, Bruna Moretto Rodrigues, Satye Shizukuda, Andrei Félix Oliveira, Miriane Oliveira, David Livingstone Alves Figueiredo, Giulianno Molina Melo, Rubens Adão Silva, Claudio Fainstein, Gerson Felisbino dos Reis, Rossana Corbo, Helton Estrela Ramos, Cléber Pinto Camacho, Fernanda Vaisman, Mário Vaisman
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:EBioMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422003188