Neuronal PAS Domain Protein 4 Suppression of Oxygen Sensing Optimizes Metabolism during Excitation of Neuroendocrine Cells

Neuronal PAS Domain Protein 4 Suppression of Oxygen Sensing Optimizes Metabolism during Excitation of Neuroendocrine Cells

Summary: Depolarization of neuroendocrine cells results in calcium influx, which induces vesicle exocytosis and alters gene expression. These processes, along with the restoration of resting membrane potential, are energy intensive. We hypothesized that cellular mechanisms exist to maximize energy p...

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Bibliographic Details
Main Authors: Paul V. Sabatini, Thilo Speckmann, Cuilan Nian, Maria M. Glavas, Chi Kin Wong, Ji Soo Yoon, Tatsuya Kin, A.M. James Shapiro, William T. Gibson, C. Bruce Verchere, Francis C. Lynn
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717318429

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http://www.sciencedirect.com/science/article/pii/S2211124717318429

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