A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila

Maintaining metabolic homeostasis during feeding and fasting states is critical to animal survival. Here the authors show that Capa hormone signaling, homologs to mammalian Neuromedin U, helps control homeostasis via regulation of nutrient uptake and energy storage in Drosophila.

Bibliographic Details
Main Authors: Takashi Koyama, Selim Terhzaz, Muhammad T. Naseem, Stanislav Nagy, Kim Rewitz, Julian A. T. Dow, Shireen A. Davies, Kenneth V. Halberg
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25445-2