Insulin receptor knockdown blocks filarial parasite development and alters egg production in the southern house mosquito, Culex quinquefasciatus.

Lymphatic filariasis, commonly known as elephantiasis, is a painful and profoundly disfiguring disease. Wuchreria bancrofti (Wb) is responsible for >90% of infections and the remainder are caused by Brugia spp. Mosquitoes of the genera Culex (in urban and semi-urban areas), Anopheles (in rural ar...

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Bibliographic Details
Main Authors: Andrew Bradley Nuss, Mark R Brown, Upadhyayula Suryanarayana Murty, Monika Gulia-Nuss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5918164?pdf=render