Triptolide attenuates irritable bowel syndrome via inhibiting ODC1

Abstract Background Irritable bowel syndrome (IBS) is a chronic disorder of the gut-brain axis with significant morbidity. Triptolide, an active compound extracted from Tripterygium wilfordii Hook F (TwHF), has been widely used as a major medicinal herb in the treatment of inflammatory disease. Meth...

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Bibliographic Details
Main Authors: Ning Zhu, Liuyan Zhu, Xueliang Zhang, Chengbin Huang, Wenjun Xiang, Bingwu Huang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-023-02847-8