Macrophages Are the Key Players in Promoting Hyper-Inflammatory Response in a Mouse Model of TB-IRIS

Macrophages Are the Key Players in Promoting Hyper-Inflammatory Response in a Mouse Model of TB-IRIS

TB-IRIS is an abnormal inflammatory response in a subset of HIV-TB co-infected patients shortly after initiation of anti-retroviral therapy (ART). Therapy in these patients could have greatly improved the life expectancy as ART reconstitutes the function and number of CD4+ T cells and many patients...

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Bibliographic Details
Main Authors: Lalit Pal, Raj Nandani, Pawan Kumar, Bharati Swami, Gargi Roy, Sangeeta Bhaskar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
TB-IRIS-tuberculosis-associated IRIS
macrophage
Mycobacterium tuberculosis
inflammation
HIV—human immunodeficiency virus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.775177/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.775177/full

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