Loss of Pten in renal tubular cells leads to water retention by upregulating AQP2

Introduction: Phosphatase and tensin (PTEN) is a multifunctional gene associated with the normal development and physiological function of various tissues including the kidney. However, its role in renal tubular reabsorption function has not been well elucidated. Methods: We generated a renal tubule...

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Bibliographic Details
Main Authors: Zhuo Sun, Xiaotong Shao, Haotian Wu, Yaxian Zhao, Yidan Cao, Danhua Li, Ying Sun, Qingling Wang
Format: Article
Language:English
Published: Karger Publishers 2022-11-01
Series:Kidney Diseases
Online Access:https://www.karger.com/Article/FullText/528010