Inferring tree causal models of cancer progression with probability raising.

Existing techniques to reconstruct tree models of progression for accumulative processes, such as cancer, seek to estimate causation by combining correlation and a frequentist notion of temporal priority. In this paper, we define a novel theoretical framework called CAPRESE (CAncer PRogression Extra...

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Bibliographic Details
Main Authors: Loes Olde Loohuis, Giulio Caravagna, Alex Graudenzi, Daniele Ramazzotti, Giancarlo Mauri, Marco Antoniotti, Bud Mishra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0108358