Farnesoid X receptor represses hepatic lipase gene expression

Farnesoid X receptor represses hepatic lipase gene expression

The farnesoid X receptor (FXR) is a nuclear receptor that regulates gene expression in response to bile acids (BAs). FXR plays a central role in BA, cholesterol, and lipoprotein metabolism. Here, we identify HL, an enzyme involved in the metabolism of remnant and high density lipoproteins, as a nove...

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Bibliographic Details
Main Authors: Audrey Sirvent, Adrie J.M. Verhoeven, Hans Jansen, Vladimir Kosykh, Raphaël J. Darteil, Dean W. Hum, Jean-Charles Fruchart, Bart Staels
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Journal of Lipid Research
Subjects:
hepatocytes
small interfering ribonucleic acids
lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341419

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http://www.sciencedirect.com/science/article/pii/S0022227520341419

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