Preparation and anti-triple-negative breast cancer cell effect of a nanoparticle for the codelivery of paclitaxel and gemcitabine

Preparation and anti-triple-negative breast cancer cell effect of a nanoparticle for the codelivery of paclitaxel and gemcitabine

Abstract Amphiphilic polymers (HA-ANI) were prepared by grafting hyaluronic acid (HA) and 6-(2-nitroimidazole)hexylamine (ANI) and then self-assemble in water to form nanoparticles (NPs) that could be loaded with paclitaxel (PTX) and gemcitabine (GEM) by dialysis. Infrared spectroscopy and 1H-NMR in...

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Bibliographic Details
Main Authors: Fan Yang, Zehui Fan, Lixia Zhang, Yanjuan He, Run Hu, Jinkun Xiang, Shiyang Fu, Guowei Wang, Jianlong Wang, Xiaojun Tao, Pan Zhang
Format: Article
Language:English
Published: Springer 2023-09-01
Series:Discover Nano
Subjects:
Triple-negative breast cancer
Paclitaxel
Gemcitabine
Nanodrug delivery system
Online Access:https://doi.org/10.1186/s11671-023-03899-1

Internet

https://doi.org/10.1186/s11671-023-03899-1

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