The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response

Abstract Fungal infections represent a major global health problem affecting over a billion people that kills more than 1.5 million annually. In this study, we employed an integrative approach to reveal the landscape of the human immune responses to Candida spp. through meta-analysis of microarray,...

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Bibliographic Details
Main Authors: Ranieri Coelho Salgado, Dennyson Leandro M. Fonseca, Alexandre H. C. Marques, Sarah Maria da Silva Napoleao, Tábata Takahashi França, Karen Tiemi Akashi, Caroline Aliane de Souza Prado, Gabriela Crispim Baiocchi, Desirée Rodrigues Plaça, Gabriel Jansen-Marques, Igor Salerno Filgueiras, Roberta De Vito, Paula Paccielli Freire, Gustavo Cabral de Miranda, Niels Olsen Saraiva Camara, Vera Lúcia Garcia Calich, Hans D. Ochs, Lena F. Schimke, Igor Jurisica, Antonio Condino-Neto, Otavio Cabral-Marques
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99838-0