Reconstitution of bacterial autotransporter assembly using purified components

Autotransporters are a superfamily of bacterial virulence factors consisting of an N-terminal extracellular (‘passenger’) domain and a C-terminal β barrel (‘β’) domain that resides in the outer membrane (OM). The mechanism by which the passenger domain is secreted is poorly understood. Here we show...

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Bibliographic Details
Main Authors: Giselle Roman-Hernandez, Janine H Peterson, Harris D Bernstein
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04234