Identification of novel genetic risk loci in Maltese dogs with necrotizing meningoencephalitis and evidence of a shared genetic risk across toy dog breeds.

Identification of novel genetic risk loci in Maltese dogs with necrotizing meningoencephalitis and evidence of a shared genetic risk across toy dog breeds.

Necrotizing meningoencephalitis (NME) affects toy and small breed dogs causing progressive, often fatal, inflammation and necrosis in the brain. Genetic risk loci for NME previously were identified in pug dogs, particularly associated with the dog leukocyte antigen (DLA) class II complex on chromoso...

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Bibliographic Details
Main Authors: Isabelle Schrauwen, Renee M Barber, Scott J Schatzberg, Ashley L Siniard, Jason J Corneveaux, Brian F Porter, Karen M Vernau, Rebekah I Keesler, Kaspar Matiasek, Thomas Flegel, Andrew D Miller, Teresa Southard, Christopher L Mariani, Gayle C Johnson, Matthew J Huentelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0112755

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https://doi.org/10.1371/journal.pone.0112755

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