Dose-Duration Reciprocity for G protein activation: Modulation of kinase to substrate ratio alters cell signaling.

In animal cells, activation of heterotrimeric G protein signaling generally occurs when the system's cognate signal exceeds a threshold, whereas in plant cells, both the amount and the exposure time of at least one signal, D-glucose, are used toward activation. This unusual signaling property c...

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Bibliographic Details
Main Authors: Kang-Ling Liao, Charles E Melvin, Rosangela Sozzani, Roger D Jones, Timothy C Elston, Alan M Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0190000