Myocardial Effects of Aldosterone Antagonism in Heart Failure With Preserved Ejection Fraction

Myocardial Effects of Aldosterone Antagonism in Heart Failure With Preserved Ejection Fraction

Background Spironolactone may have prognostic benefit in selected patients with heart failure with preserved ejection fraction. This study assessed the myocardial tissue effects of spironolactone in heart failure with preserved ejection fraction. Methods and Results A 1:1 randomized controlled study...

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Bibliographic Details
Main Authors: Adam K. McDiarmid, Peter P. Swoboda, Bara Erhayiem, Katrina A. Bounford, Petra Bijsterveld, Keith Tyndall, Graham J. Fent, Pankaj Garg, Laura E. Dobson, Tarique A. Musa, James R. J. Foley, Klaus K. Witte, Mark T. Kearney, John P. Greenwood, Sven Plein
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiovascular magnetic resonance
extracellular volume
heart failure
heart failure with preserved ejection fraction
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.011521

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.011521

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