Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2

Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2

Background: Antibodies raised against human seasonal coronaviruses (sCoVs), which are responsible for the common cold, are known to cross-react with SARS-CoV-2 antigens. This prompts questions about their protective role against SARS-CoV-2 infections and COVID-19 severity. However, the relationship...

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Bibliographic Details
Main Authors: Yannick Galipeau, Vinayakumar Siragam, Geneviève Laroche, Erika Marion, Matthew Greig, Michaeline McGuinty, Ronald A Booth, Yves Durocher, Miroslava Cuperlovic-Culf, Steffany A.L. Bennett, Angela M. Crawley, Patrick M. Giguère, Curtis Cooper, Marc-André Langlois
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:EBioMedicine
Subjects:
SARS-CoV-2
COVID-19
OC43
NL63
seasonal coronavirus
human coronaviruses
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421004941

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http://www.sciencedirect.com/science/article/pii/S2352396421004941

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