A new osteogenic protein isolated from Dioscorea opposita Thunb accelerates bone defect healing through the mTOR signaling axis

A new osteogenic protein isolated from Dioscorea opposita Thunb accelerates bone defect healing through the mTOR signaling axis

Delayed bone defect repairs lead to severe health and socioeconomic impacts on patients. Hence, there are increasing demands for medical interventions to promote bone defect healing. Recombinant proteins such as BMP-2 have been recognized as one of the powerful osteogenic substances that promote mes...

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Bibliographic Details
Main Authors: John Akrofi Kubi, Augustine Suurinobah Brah, Kenneth Man Chee Cheung, Yin Lau Lee, Kai-Fai Lee, Stephen Cho Wing Sze, Wei Qiao, Kelvin Wai-Kwok Yeung
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Bioactive Materials
Subjects:
Dioscorea spp protein
Mesenchymal stem cells (MSCs)
Osteoblast differentiation
Bone mineral density (BMD)
Bone defect repair
mTOR signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23001366

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http://www.sciencedirect.com/science/article/pii/S2452199X23001366

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