Pretransplant, Th17 dominant alloreactivity in highly sensitized kidney transplant candidates

Pretransplant, Th17 dominant alloreactivity in highly sensitized kidney transplant candidates

IntroductionSensitization to donor human leukocyte antigen (HLA) molecules prior to transplantation is a significant risk factor for delayed access to transplantation and to long-term outcomes. Memory T cells and their cytokines play a pivotal role in shaping immune responses, thereby increasing the...

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Bibliographic Details
Main Authors: Sarita Negi, Alissa K. Rutman, Chee Loong Saw, Steven Paraskevas, Jean Tchervenkov
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Transplantation
Subjects:
transplantation
highly sensitized
sensitization
Th17 cells
alloreactivity
mixed leukocyte reaction
Online Access:https://www.frontiersin.org/articles/10.3389/frtra.2024.1336563/full

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https://www.frontiersin.org/articles/10.3389/frtra.2024.1336563/full

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