Overexpression of vascular endothelial growth factor enhances the neuroprotective effects of bone marrow mesenchymal stem cell transplantation in ischemic stroke

Overexpression of vascular endothelial growth factor enhances the neuroprotective effects of bone marrow mesenchymal stem cell transplantation in ischemic stroke

Although bone marrow mesenchymal stem cells (BMSCs) might have therapeutic potency in ischemic stroke, the benefits are limited. The current study investigated the effects of BMSCs engineered to overexpress vascular endothelial growth factor (VEGF) on behavioral defects in a rat model of transient c...

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Bibliographic Details
Main Authors: Cui Liu, Zhi-Xiang Yang, Si-Qi Zhou, Ding Ding, Yu-Ting Hu, Hong-Ning Yang, Dong Han, Shu-Qun Hu, Xue-Mei Zong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
bone marrow mesenchymal stem cell; brain-derived neurotrophic factor; cd31; microtubule associated protein 2; middle cerebral artery occlusion; stroke; transplantation; vascular endothelial growth factor
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=6;spage=1286;epage=1292;aulast=Liu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=6;spage=1286;epage=1292;aulast=Liu

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