Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway

Nowadays, although chemotherapy is an established therapy for breast cancer, the molecular mechanisms of chemotherapy resistance in breast cancer remain poorly understood. This study aims to explore the effects of endoplasmic reticulum stress on autophagy, apoptosis, and chemotherapy resistance in h...

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Bibliographic Details
Main Authors: Jia-Teng Zhong, Jian Yu, Hai-Jun Wang, Yu Shi, Tie-Suo Zhao, Bao-Xia He, Bin Qiao, Zhi-Wei Feng
Format: Article
Language:English
Published: IOS Press 2017-04-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317697562