Pharmacogenomics, CYP2D6, and Tamoxifen: A Survey of the Reasons Sustaining European Clinical Practice Paradigms

Tamoxifen is a drug that is often used in the clinical management of breast cancer. CYP2D6 is a key metabolizing enzyme that is involved in the conversion of tamoxifen to its active drug metabolites. CYP2D6 has several alleles that metabolize tamoxifen and other drugs at different rates that can alt...

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Bibliographic Details
Main Authors: Sara S. Reis, Ana S. Carvalho, Rúben Fernandes
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/55/7/344