Fathers’ preconception smoking and offspring DNA methylation

Fathers’ preconception smoking and offspring DNA methylation

Abstract Background Experimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. We aim to identify epigenetic marks in offspring associated with father’s...

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Bibliographic Details
Main Authors: Negusse Tadesse Kitaba, Gerd Toril Mørkve Knudsen, Ane Johannessen, Faisal I. Rezwan, Andrei Malinovschi, Anna Oudin, Bryndis Benediktsdottir, David Martino, Francisco Javier Callejas González, Leopoldo Palacios Gómez, Mathias Holm, Nils Oskar Jõgi, Shyamali C. Dharmage, Svein Magne Skulstad, Sarah H. Watkins, Matthew Suderman, Francisco Gómez-Real, Vivi Schlünssen, Cecilie Svanes, John W. Holloway
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Clinical Epigenetics
Subjects:
Preconception
Paternal effects
Tobacco smoke
Epigenetic
Epigenome-wide association study
DNA methylation
Online Access:https://doi.org/10.1186/s13148-023-01540-7

Internet

https://doi.org/10.1186/s13148-023-01540-7

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