Formulation and Evaluation of Prednisolone Sodium Metazoate-Loaded Mucoadhesive Quatsomal Gel for Local Treatment of Recurrent Aphthous Ulcers: Optimization, In Vitro, Ex Vivo, and In Vivo Studies

Formulation and Evaluation of Prednisolone Sodium Metazoate-Loaded Mucoadhesive Quatsomal Gel for Local Treatment of Recurrent Aphthous Ulcers: Optimization, In Vitro, Ex Vivo, and In Vivo Studies

This study aims to formulate a buccal mucoadhesive gel containing prednisolone sodium metazoate-loaded quatsomes for efficient localized therapy of recurrent aphthous ulcers. Quatsomes were prepared using a varied concentration of quaternary ammonium surfactants (QAS) and cholesterol (CHO). A 2<s...

Full description

Bibliographic Details
Main Authors: Ashraf Kassem, Hanan Refai, Mohamed A. El-Nabarawi, Menna M. Abdellatif
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
recurrent aphthous ulcer
buccal mucoadhesive gel
quatsomes
prednisolone sodium metazoate
Online Access:https://www.mdpi.com/1999-4923/15/7/1947

Internet

https://www.mdpi.com/1999-4923/15/7/1947

Similar Items