Antioxidants positively regulate obesity dependent circRNAs - sperm quality - functional axis

Antioxidants positively regulate obesity dependent circRNAs - sperm quality - functional axis

Obesity is a pathophysiological condition, dependent on body fat accumulation, that progressively induces systemic oxidative stress/inflammation leading to a set of associated clinical manifestations, including male infertility. CircRNAs, covalently closed RNA molecules, are key regulators of sperm...

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Bibliographic Details
Main Authors: Vincenza Grazia Mele, Teresa Chioccarelli, Rosario Finamore, Antonella D’Agostino, Maria d’Agostino, Donatella Cimini, Monica Mattia, Veronica Porreca, Andrea Maria Giori, Silvia Fasano, Gilda Cobellis, Chiara Schiraldi, Rosanna Chianese, Francesco Manfrevola
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
antioxidant agents
backsplicing
circRNAs
male infertility
obesity
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1290971/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1290971/full

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