Comparison of explanatory and pragmatic design choices in a cluster-randomized hypertension trial: effects on enrollment, participant characteristics, and adherence

Comparison of explanatory and pragmatic design choices in a cluster-randomized hypertension trial: effects on enrollment, participant characteristics, and adherence

Abstract Background Explanatory trials are designed to assess intervention efficacy under ideal conditions, while pragmatic trials are designed to assess whether research-proven interventions are effective in “real-world” settings without substantial research support. Methods We compared two trials...

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Bibliographic Details
Main Authors: Karen L. Margolis, A. Lauren Crain, Beverly B. Green, Patrick J. O’Connor, Leif I. Solberg, MarySue Beran, Anna R. Bergdall, Pamala A. Pawloski, Jeanette Y. Ziegenfuss, Meghan M. JaKa, Deepika Appana, Rashmi Sharma, Amy J. Kodet, Nicole K. Trower, Daniel J. Rehrauer, Zeke McKinney, Christine K. Norton, Patricia Haugen, Jeffrey P. Anderson, Benjamin F. Crabtree, Sarah K. Norman, JoAnn M. Sperl-Hillen
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Trials
Subjects:
Hypertension
Self-measured blood pressure
Telemonitoring
Pharmacist care
Pragmatic trials
Online Access:https://doi.org/10.1186/s13063-022-06611-3

Internet

https://doi.org/10.1186/s13063-022-06611-3

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