Psoralen Inactivation of Viruses: A Process for the Safe Manipulation of Viral Antigen and Nucleic Acid

Psoralen Inactivation of Viruses: A Process for the Safe Manipulation of Viral Antigen and Nucleic Acid

High consequence human pathogenic viruses must be handled at biosafety level 2, 3 or 4 and must be rendered non-infectious before they can be utilized for molecular or immunological applications at lower biosafety levels. Here we evaluate psoralen-inactivated Arena-, Bunya-, Corona-, Filo-, Flavi- a...

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Bibliographic Details
Main Authors: Katherine Schneider, Loni Wronka-Edwards, Melissa Leggett-Embrey, Eric Walker, Peifang Sun, Brian Ondov, Travis H. Wyman, MJ Rosovitz, Sherry S. Bohn, James Burans, Tadeusz Kochel
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Viruses
Subjects:
virus
inactivation
biocontainment
BSL-4
BSL-3
psoralen
Trizol LS
IFA
safety
biosafety
PCR
reverse transcription
sequencing
antibody
sterility
Online Access:http://www.mdpi.com/1999-4915/7/11/2912

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http://www.mdpi.com/1999-4915/7/11/2912

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